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Anion Exchange Protein 1, Erythrocyte. englanti. AE1 Anion Exchanger. AE1 Chloride Bicarbonate Exchanger. AE1 Chloride-Bicarbonate Exchanger.

Made to Order. Catalog # 4390771 Standard | 5 nmol : … CD47 blockade triggers T cell–mediated destruction of immunogenic tumors. Nature medicine, 2015, 21(10): 1209-1215. Soto-Pantoja D R, et al. CD47 signaling pathways controlling cellular differentiation and responses to stress.

Cd47 gene

Reproducible results in bioactivity assays. Learn More 5 Mar 2021 CD47 (CD47 Molecule) is a Protein Coding gene. Diseases associated with CD47 include Hereditary Spherocytosis and Neonatal Meningitis. Product Specific Information. Description: The monoclonal antibody B6H12 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 19 Jan 2017 Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Gene: Cd47 - ENSMUSG00000055447 - Mus musculus (mouse) General information. Ensembl ID: ENSMUSG00000055447: Name: Cd47: Description Description: Homo sapiens CD47 molecule (CD47), transcript variant 1, mRNA.

Vid flödescytometri kan CD47 och/eller färgämnet eosin-5´-maleimid användas för att detektera Genes och orsak till variabilitet i symtom är oklart. Image: Vad

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets Triple knockout mice do not express the recombination activating gene 2 (Rag2), the CD47 antigen (CD47) gene, or the X-linked interleukin 2 receptor, gamma chain (Il2rg) gene. These mice are viable and fertile. These mice contain no T cells, B cell, or Natural Killer (NK) cells. development of antisense strategies to locally or globally suppress CD47 gene expression.

Abstract. Integrin-associated protein (IAP or CD47) is a receptor for thrombospondin family members, a ligand for the transmembrane signaling protein SIRPα and

Transcriptional control of the CD47 gene is incompletely understood and has only been studied in the context of neuronal development, where transcription of CD47 and concomitant neurite outgrowth relies on the transcription factor α-Pal/NRF-1 (Chang and Huang, 2004; Chang et al., 2005). NCBI Description of CD47 This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. cell lines with CD47 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with CD47 gene/protein from the curated CTD Gene-Chemical Interactions dataset. Cd47 Gene Detail Summary Symbol.

Methods: After the lentiviral CD47-siRNA was transfected into acute myelogenous leukemia stem cells (LSCs), the proliferative status of acute myelogenous LSCs was detected by cell counting kit-8, and the apoptosis of stem cells of acute myeloid leukemia was detected by … Gene information about ENSG00000196776 / CD47 - CD47 molecule. Gene name.
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S9). In a nuclear run-on assay with P493-6 cells, MYC induced expression of the CD47 gene, along with other well-known target genes such as PDK1, CHEK1, CDK2, LDHA, and ODC1 (fig.

To investigate the effect of targeted inhibition of CD47 gene expression on stem cell clearance in acute myeloid leukemia. Methods.
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CD47 (Cluster of Differentiation 47) also known as integrin associated protein ( IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.

Antibody staining with HPA044659 and CAB016055 in immunohistochemistry. Gene name. CD47 (HGNC Symbol) Synonyms.

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CD47 is similar to these genes: Galectin-3, Dermatopontin, BCAR1 and more.

Gene Symbol, Annotation, Raw Average WT Counts, Converted WT1 TPM, Converted Cd47, CD47 antigen (Rh-related antigen, integrin-associated signal 52, RP11-74C13.3, Normalizer.

19 Jan 2017 Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Table S8 - Wildtype Proliferative Zone Gene Expression Signature. GenBank Accession AK164165, Cd47, 3.20, 10.66, 0.049. NM_016957, Hmgn2, 3.20 CD47 is the latest immuno-oncology target and multiple companies are 076 - Krystal Biotech's NOVEL Gene Therapy for Rare Diseases | Interview with WX Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet Defining the role of CD47 and SIRPα in murine B cell homeostasis. RNA/DNA extraction, reporter gene assays and gene expression profiling. cells and macrophages via inflammatory mediators and CD47 promotes tumour cell Acta Endocrinologica - 2018-01-01. SNX10 gene mutation leading to osteopetrosis with dysfunctional CD47/SIRPalpha-interaction. Pernilla Lundberg, Cecilia >sp|A0A885|PIP_GORGO Prolactin-inducible protein homolog OS=Gorilla gorilla Uncharacterized protein OS=Gorilla gorilla gorilla GN=CD47 PE=4 SV=1 >W141097699 · AVHA01000109, Firmicutes, Peptoclostridium difficile CD47 [AVHA], 46727, 46653, -, Thr, TGT, [ENA], ○.

Soto-Pantoja D R, et al. CD47 signaling pathways controlling cellular differentiation and responses to stress. Critical reviews in biochemistry and … Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.